Wnt antagonists and methods of treatment and screening

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United States of America Patent

PATENT NO 9157904
SERIAL NO

13005214

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Abstract

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The present invention relates to compositions comprising Wnt antagonists and methods of treating Wnt-associated diseases and disorders, such as cancer, inducing differentiation, and reducing the frequency of cancer stem cells, as well as novel methods of screening for such Wnt antagonists. In particular, the invention discloses soluble FZD, SFRP and Ror receptors and their use.

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Patent Owner(s)

  • ONCOMED PHARMACEUTICALS, INC.

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gurney, Austin L San Francisco, US 2150 9982
Mitra, Satyajit Sujit Kumar South Pasadena, US 11 148
Satyal, Sanjeev H San Carlos, US 18 203

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