IDO inhibitors

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 9174942
APP PUB NO 20140323740A1
SERIAL NO

14264974

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Presently provided are compounds according to the formula (I) or (II), and pharmaceutical compositions comprising the compounds, wherein R1, R4, and R5 are defined herein. Such compounds and compositions are useful for modulating an activity of indoleamine 2,3-dioxygenase; treating indoleamine 2,3-dioxygenase (IDO) mediated immunosuppression; treating a medical conditions that benefit from the inhibition of enzymatic activity of indoleamine-2,3-dioxygenase; enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent; treating tumor-specific immunosuppression associated with cancer; and treating immunosuppression associated with an infectious disease.

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Patent Owner(s)

Patent OwnerAddress
NEWLINK GENETICS CORPORATION2503 SOUTH LOOP DRIVE AMES IA 50010

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Jaipuri, Firoz Ames, US 25 281
Kesharwani, Tanay Lake Katrine, US 10 207
Kumar, Sanjeev Ames, US 243 5085
Lalonde, Judith Bryn Mawr, US 2 35
Link, Charles J Clive, US 10 98
Malachowski, William Bryn Mawr, US 6 195
Mautino, Mario R Ankeny, US 12 109
Muller, Alexander Wynnewood, US 65 950
Prendergast, George Wynnewood, US 3 35
Vahanian, Nicholas N Polk City, US 10 78
Waldo, Jesse Huxley, US 18 244

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