Method of regulating fertilizing ability using cyclic ADP-ribose and CD38
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United States of America Patent
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Nov 10, 2015
Grant Date -
Aug 29, 2013
app pub date -
Mar 4, 2013
filing date -
Jan 25, 2011
priority date (Note) -
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Abstract
The present invention relates to a pharmaceutical composition for promoting fertilization comprising cyclic ADP-ribose or its derivative, CD38 and to a method of promoting fertilization by promoting the synthesis of cyclic ADP-ribose to increase sperm motility. Also, the present invention relates to a pharmaceutical composition for contraception and a method for inhibiting fertilization, which can inhibit the expression or function of cyclic ADP-ribose to reduce sperm motility, thereby inhibiting fertilization.
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