Targeted delivery using tissue-specific peptidomimetic ligands

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United States of America Patent

PATENT NO 9181225
SERIAL NO

13664288

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Abstract

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Compositions and methods for tissue-specific targeted delivery of therapeutic agents through the use of tissue-specific peptidomimetic ligands are disclosed herein. The ligand comprises a composition of formula A-scaffold-A′ and one or more hydrophobic anchors covalently linked to the scaffold. The A and A′ compounds linked to the scaffold comprise monovalent peptidomimetic compounds wherein each monovalent peptidomimetic compound is selected from the group consisting of fragments IKs, GKs, IDs, GSs, GTs, VSs, TKs, KTs, ARs, KIs, KEs, AEs, GRs, YSs, IRs, and morpholino.

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Patent Owner(s)

Patent OwnerAddress
GRADALIS INC2001 BRYAN STREET SUITE 2050 DALLAS TX 75201

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Templeton, Nancy Smyth Houston, US 15 58

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