N-substituted mannosamine derivatives, process for their preparation and their use

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United States of America Patent

PATENT NO 9187513
APP PUB NO 20140046051A1
SERIAL NO

14111131

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Abstract

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A compound of the formula (1) wherein R1 is a group removable by hydrogenolysis, and wherein R2 is OH or R2 is —NHR3 wherein R3 is a group removable by hydrogenolysis. The compound can be made from fructose by a Heyns-rearrangement. The compound can be used then to make free D-mannosamine or its salts, D-mannosamine building blocks and mannosamine containing oligo- or polysaccharides, N-acetyl-D-mannosamine and its hydrates and solvates, neuraminic acid derivatives, and viral neuraminidase inhibitors.

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Patent OwnerAddress
GLYCOM A/S2970 HØRSHOLM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dekany, Gyula Sinnamon Park, AU 74 103
Hederos, Markus Svedala, SE 25 23
Jánosi, Ågnes Budapest, HU 1 0
Röhrig, Christoph Mühlingen, DE 12 11
Vrasidas, Ioannis Salonika, GR 11 13

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