Determination of neuropsychiatric therapy mechanisms of action

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United States of America Patent

PATENT NO 9198612
SERIAL NO

12169350

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Abstract

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A computer implemented method, apparatus, and computer program product of determining mechanisms of action for therapies. A first set of brain scans for each subject in a plurality of subjects generated at a first time period and a second set of brain scans for each subject generated at a second time period are received. Each subject is diagnosed with a given condition and received a given therapy. A set of changes in the set of brain scans is identified for the each subject based on a comparison of a first set of regions of interest in the first set of scans for each subject with a second set of regions of interest in the second set of scans for each subject. A set of typical changes attributable to the given therapy is identified. A mechanism of action for the given therapy is generated based on the set of typical changes.

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Patent Owner(s)

Patent OwnerAddress
INTERNATIONAL BUSINESS MACHINES CORPORATIONNEW ORCHARD ROAD ARMONK NY 10504

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Angell, Robert Lee Salt Lake City, US 75 3713
Friedlander, Robert R Southbury, US 254 7047
Fueyo, Joanna Lynn Brighton, US 13 226
Kraemer, James R Santa Fe, US 320 9630

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