Oligomers

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United States of America Patent

PATENT NO 9243251
SERIAL NO

13909132

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Abstract

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Molecules are provided for inducing or facilitating exon skipping in forming spliced mRNA products from pre-mRNA molecules in cells. The molecules may be provided directly as oligonucleotides or expression products of vectors that are administered to a subject. High rates of skipping can be achieved. High rates of skipping reduce the severity of a disease like Duchene Muscular Dystrophy so that the disease is more like Becker Muscular Dystrophy. This is a severe reduction in symptom severity and mortality.

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Patent Owner(s)

Patent OwnerAddress
ROYAL HOLLOWAY UNIVERSITY OF LONDONEGHAM SURREY TW20 0EX

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dickson, John George Surrey, GB 21 846
Graham, Ian Cambridge, GB 21 834
Popplewell, Linda Surrey, GB 15 779

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