Suture-specific coatings for modulated release of bioactive agents
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United States of America Patent
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Feb 2, 2016
Grant Date -
May 1, 2008
app pub date -
Oct 30, 2007
filing date -
Oct 30, 2006
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Abstract
Suture-specific coatings having a number average molecular weight not exceeding 20 kDa, a melting temperature above 37° C., and heat of fusion exceeding 20 J/g, are formed of copolyesters of polycaprolactone or of ε-caprolactone and at least one cyclic monomer forming a segmented polyester chain initiated by a polyaxial crystalline organic compound or an amorphous polyaxial polymeric initiator and include from about 0.01 to about 10 weight percent of at least one molecularly dispersed bioactive agent.
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