Recombinant microorganisms having phosphoketolase activity and diminished phosphofructokinase activity and/or glucose-6 phosphate dehydrogenase activity

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United States of America Patent

PATENT NO 9249430
APP PUB NO 20140248669A1
SERIAL NO

14232011

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Described are recombinant microorganisms characterized by having phosphoketolase activity, having a diminished or inactivated Embden-Meyerhof-Parnas pathway (EMPP) by inactivation of the gene(s) encoding phosphofructokinase or by reducing phosphofructokinase activity as compared to a non-modified microorganism and having a diminished or inactivated oxidative branch of the pentose phosphate pathway (PPP) by inactivation of the gene(s) encoding glucose-6-phosphate dehydrogenase or by reducing glucose-6-phosphate dehydrogenase activity as compared to a non-modified microorganism. These microorganisms can be used for the production of useful metabolites such as acetone, isobutene or propene.

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Patent OwnerAddress
SCIENTIST OF FORTUNE S A7A RUE DES GLACIS LUXEMBOURG L-1628

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Marliere, Philippe Mouscron, BE 48 192

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