Sensor device with imaging optics

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United States of America Patent

PATENT NO 9250181
APP PUB NO 20120262565A1
SERIAL NO

13498347

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ATTORNEY / AGENT: (SPONSORED)

Importance

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Abstract

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The invention relates to a method and a sensor device (100) for detecting particles (MP) that are bound to the binding surface (12) of a carrier (11). The sensor device (100) comprises a microscope (50) for imaging bound particles (MP) onto an image sensor (53). In order to increase the spatial resolution of the microscope (50), a displacement unit (60,70,80) is provided that can displace the carrier (11) relative to the image sensor (53). The distance of a bound particle (MP) from the binding surface (12) and/or its lateral displacement in reaction to forces can thus be determine with high accuracy. This allows to discriminate specific bindings of large magnetic particles (MP) that are bound to the binding surface (12) via smaller target particles from nonspecific direct bindings.

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Patent Owner(s)

  • KONINKLIJKE PHILIPS ELECTRONICS N.V.

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kahlman, Josephus Arnoldus Henricus Maria Tilburg, NL 112 728
Van, Zon Joannes Baptist Adrianus Dionisius Waalre, NL 24 185

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