Method and apparatus for estimating a molecular mass parameter in a sample
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United States of America Patent
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Feb 2, 2016
Grant Date -
Sep 12, 2013
app pub date -
Sep 5, 2012
filing date -
Sep 5, 2011
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Abstract
A method for estimating a molecular mass parameter in a sample that includes at least one component of given molecular mass, comprising the steps consisting of passing the sample through a processing chain comprising a mass spectrometer with a MEMS or NEMS electromechanical sensor, in this way obtaining a signal representing the molecular mass parameter and estimating the molecular mass parameter by means of a signal processing device. The molecular mass parameter is defined on the basis of a parameter of time distribution of successive detections, by the MEMS or NEMS electromechanical sensor, of the adsorption of said component, and the estimation of the molecular mass parameter is made by Bayesian inference, on the basis of a direct analytical modeling of said signal according to the molecular mass parameter and to technical parameters of the processing chain comprising at least one technical parameter of the MEMS or NEMS electromechanical sensor.
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