Quantitative assessment of biological impact using overlap methods
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United States of America Patent
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Feb 2, 2016
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N/A
app pub date -
Jan 6, 2014
filing date -
Jan 4, 2013
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Abstract
Scores for particular network models (those having a source node connected to a set of measurable downstream nodes via causal edges) are computed across multiple networks by accounting for an overlap between these models in a manner that reduces cross-network redundancy and increases the specificity of the network models for the network in which they are found. According to another aspect, a meta-network model is created for networks by accounting for the occurrence of network models that are found in multiple networks in a manner that reduces the redundancy across networks and that increases the specificity of the network model score. Preferably, this process provides additional weighting factors for each node in the network model.
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