Targeted genomic modification with partially single-stranded donor molecules

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United States of America Patent

PATENT NO 9255259
SERIAL NO

12931760

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Abstract

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Disclosed herein are donor molecules comprising single-stranded complementary regions flanking one or more sequences of interest. The donor molecules and/or compositions comprising these molecules can be used in methods for targeted integration of an exogenous sequence into a specified region of interest in the genome of a cell.

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Patent Owner(s)

  • SANGAMO BIOSCIENCES, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cost, Gregory J Berkeley, US 27 1547
Guschin, Dmitry M Albany, US 5 425
Urnov, Fyodor Richmond, US 106 4576

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