Methods for modulating D1-D2 dopamine receptor coupling and function

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United States of America Patent

PATENT NO 9266954
APP PUB NO 20130202600A1
SERIAL NO

13862010

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Abstract

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The present invention provides for prevention and/or treatment of neurological or neuropsychiatric disorders involving abnormal D1-D2 dopamine receptor coupling and/or activation. Methods and agents are provided for modulating dopamine receptor function arising from D1-D2 coupling and/or activation. Agents of the present invention include fragments of D2 receptor or D1 receptor that can disrupt D1-D2 coupling.

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Patent Owner(s)

Patent OwnerAddress
CENTRE FOR ADDICTION AND MENTAL HEALTH100 STOKES STREET BELL GATEWAY BUILDING 6TH FLOOR TORONTO M6J 1H4

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Liu, Fang Mississauga, CA 304 1425
Pei, Lin Toronto, CA 15 24

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