Methods for producing secreted polypeptides having biological activity

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United States of America Patent

PATENT NO 9273104
APP PUB NO 20140142278A1
SERIAL NO

14081340

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Abstract

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The present invention relates to methods for producing a polypeptide having biological activity, comprising: (a) cultivating a fungal host cell in a medium conducive for the production of the polypeptide, wherein the fungal host cell comprises a first polynucleotide encoding the polypeptide operably linked to a second polynucleotide encoding a variant signal peptide or a variant prepropeptide; and (b) isolating the secreted polypeptide having biological activity from the cultivation medium.

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Patent Owner(s)

  • NOVOZYMES A/S;NOVOZYMES, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bjornvad, Mads Virum, DK 3 2
Yaver, Debbie Davis, US 77 224

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