Synthetic microfluidic systems for wound healing and hemostasis

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United States of America Patent

PATENT NO 9291614
SERIAL NO

14202721

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Abstract

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A method of assaying wound healing can include: growing cells on the matrix in the first flow channel; introducing an agent that removes the matrix from the junction; introducing a matrix material into the second flow channel so as to form the second matrix in the second flow channel and junction; and detecting cellular migration into the junction onto the second matrix. The agent that removes the matrix can include a biomolecule or chemical agent. The method can include removing cells in the matrix in the junction before introducing the matrix material into the second flow channel. A bioactive agent can be introduced into the junction to determine if it modulates cellular migration and/or clot formation into the intersection openings of tissue and vascular channels.

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Patent Owner(s)

Patent OwnerAddress
SYNVIVO INC601 GENOME WAY STE 2023E HUNTSVILLE AL 35806

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Pant, Kapil Madison, US 27 187
Prabhakarpandian, Balabhaskar Madison, US 29 133

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