High-affinity small molecule formylpeptide receptor ligands from screening of combinatorial mixture-based libraries

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United States of America Patent

PATENT NO 9310364
SERIAL NO

14174564

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Abstract

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The present invention provides novel methods and assays for high-throughput screening of combinatorial libraries to identify FPR1 and/or FPR2 ligands (e.g., agonists and/or antagonists), preferably FPR1 agonists and/or FPR2 antagonists, by positional scanning deconvolution.

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Patent Owner(s)

Patent OwnerAddress
TORREY PINES INSTITUTE FOR MOLECULAR STUDIES3550 GENERAL ATOMICS COURT SAN DIEGO CA 92121-1122

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Appel, Jon R Cardiff, US 3 9
Edwards, Bruce S Albuquerque, US 23 351
Giulianotti, Marc A Vero Beach, US 3 9
Houghten, Richard A Vero Beach, US 84 1963
Medina-Franco, Jose Port St Lucie, US 2 3
Pinilla, Clemencia Cardiff, US 32 400
Sklar, Larry A Albuquerque, US 58 580

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