Mitochondrial aldehyde dehydrogenase-2 modulators and methods of use thereof

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United States of America Patent

PATENT NO 9315484
APP PUB NO 20150105456A1
SERIAL NO

14520098

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Abstract

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The present invention provides compounds that function as modulators of mitochondrial aldehyde dehydrogenase-2 (ALDH2) activity; and pharmaceutical compositions comprising the compounds. The present invention provides therapeutic methods involving administering a subject compound, or a subject pharmaceutical composition. The present invention further provides assays for identifying agonists of ALDH2.

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Patent Owner(s)

  • THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY;THE BOARD OF TRUSTEES—LELAND STANFORD JUNIOR UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Che-Hong Fremont, US 27 168
Mochly-Rosen, Daria Menlo Park, US 77 610
Ouyang, Xiaohu Fremont, US 16 186

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