Compositions and methods for detecting cancer

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United States of America Patent

PATENT NO 9315867
SERIAL NO

12939801

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Abstract

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The present invention provides methods and compositions involving detecting the presence of and/or assessing the risk of cancer in a subject. These methods include methods of detecting and diagnosing cancer in an individual; methods of identifying individuals at risk of developing a cancer; and methods of staging a cancer. The methods generally involve detecting a palladin gene nucleotide sequence alteration that has been found to be associated with cancer and/or detecting a level of a palladin mRNA and/or protein in a biological sample. The present invention further provides nucleic acid probes, nucleic acid primers, and antibodies, as well as kits comprising one or more of the same, for use in a subject method.

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Patent Owner(s)

  • THE CLEVELAND CLINIC FOUNDATION;THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL;UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION;UNIVERSITY OF WASHINGTON

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brentnall, Teresa A Seattle, US 3 0
Bronner, Mary Patricia Moreland Hills, US 2 0
Chen, Ru Seattle, US 14 13
Otey, Carol A Chapel Hill, US 2 0
Pogue-Geile, Katherine L Pittsburgh, US 2 0
Whitcomb, David C Allison Park, US 3 0

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