Diagnostic method using PALB2

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United States of America Patent

PATENT NO 9315868
APP PUB NO 20120034318A1
SERIAL NO

13254610

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Abstract

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The present invention provides a method for detecting mutations in the PALB2 gene in pancreatic cancer patients and in individuals having a family history of pancreatic cancer. Methods are also provided for diagnosing a predisposition to pancreatic cancer, for predicting a patient's response to pancreatic cancer therapies, and for treating pancreatic cancer, based on presence of a PALB2 mutation or abberant PALB2 gene expression in a patient.

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Patent Owner(s)

  • THE JOHNS HOPKINS UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Eshleman, James R Lutherville, US 9 62
Goggins, Michael Baltimore, US 5 81
Hidalgo, Manuel Baltimore, US 69 306
Hruban, Ralph Baltimore, US 21 48
Jones, Sian Baltimore, US 25 87
Kern, Scott Hunt Valley, US 5 17
Kinzler, Kenneth W Baltimore, US 281 4771
Klein, Alison Baltimore, US 3 3
Parsons, D Williams Ellicott City, US 18 77
Velculescu, Victor E Dayton, US 28 290
Vogelstein, Bert Baltimore, US 323 6299

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