HMGN2 peptides and related molecules that selectively home to tumor blood vessels and tumor cells

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United States of America Patent

PATENT NO 9320810
APP PUB NO 20150031851A1
SERIAL NO

14067858

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Abstract

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The present invention provides a conjugate which contains a therapeutic moiety linked to a homing molecule that selectively homes to tumor blood vessels and tumor cells and that specifically binds the receptor bound by peptide KDEPQRRSARLSAKPAPPKPEPKPKKAPAKK (SEQ ID NO: 9). Methods of directing a conjugate of the invention to tumor blood vessels and tumor cells and of using a conjugate to treat cancer also are provided.

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Patent Owner(s)

  • SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Christian, Sven San Diego, US 14 40
Porkka, Kimmo Helsinki, FI 8 69
Ruoslahti, Erkki Rancho Santa Fe, US 115 2302

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