Methods for catheter-based renal neuromodulation

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United States of America Patent

PATENT NO 9327122
SERIAL NO

14611651

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Abstract

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Methods and apparatus are provided for monopolar neuromodulation, e.g., via a pulsed electric field. Such monopolar neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, monopolar neuromodulation is applied to neural fibers that contribute to renal function. In some embodiments, such monopolar neuromodulation is performed bilaterally.

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Patent Owner(s)

  • MEDTRONIC ARDIAN LUXEMBOURG S.A.R.L.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Deem, Mark Mountain View, US 159 17334
Gelfand, Mark New York, US 302 31182
Gifford,, III Hanson Woodside, US 133 14795
Levin, Howard R Teaneck, US 172 26164
Zadno, Nicolas Fremont, US 60 11716
Zarins, Denise Saratoga, US 146 9136

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