Single cell gene expression for diagnosis, prognosis and identification of drug targets

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United States of America Patent

PATENT NO 9329170
APP PUB NO 20100255471A1
SERIAL NO

12657457

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Abstract

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Methods are provided for diagnosis and prognosis of disease by analyzing expression of a set of genes obtained from single cell analysis. Classification allows optimization of treatment, and determination of whether on whether to proceed with a specific therapy, and how to optimize dose, choice of treatment, and the like. Single cell analysis also provides for the identification and development of therapies which target mutations and/or pathways in disease-state cells.

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Patent Owner(s)

  • THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Clarke, Michael F Palo Alto, US 65 2949
Dalerba, Piero D Palo Alto, US 7 263
Diehn, Maximilian Stanford, US 28 665
Kalisky, Tomer Palo Alto, US 5 260
Leyrat, Anne San Carlos, US 2 199
Liu, Huiping Chicago, US 18 284
Quake, Stephen R Stanford, US 279 17341
Wang, Jianbin Stanford, US 53 1128

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