Binding molecules for BCMA and CD3

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 9340621
APP PUB NO 20130156769A1
SERIAL NO

13678247

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Abstract

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The present invention relates to a binding molecule which is at least bispecific comprising a first and a second binding domain, wherein the first binding domain is capable of binding to epitope cluster 3 of BCMA, and the second binding domain is capable of binding to the T cell CD3 receptor complex. Moreover, the invention provides a nucleic acid sequence encoding the binding molecule, a vector comprising said nucleic acid sequence and a host cell transformed or transfected with said vector. Furthermore, the invention provides a process for the production of the binding molecule of the invention, a medical use of said binding molecule and a kit comprising said binding molecule.

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Patent Owner(s)

Patent OwnerAddress
AMGEN INCONE AMGEN CENTER DRIVE THOUSAND OAKS CA 91320-1799

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Adam, Paul Ingelheim am Rhein, DE 39 507
Borges, Eric Ingelheim am Rhein, DE 52 731
Hebeis, Barbara Ingelheim am Rhein, DE 10 221
Hipp, Susanne Ingelheim am Rhein, DE 14 203
Hoffmann, Patrick Munich, DE 69 1097
Kischel, Roman Munich, DE 43 1316
Kufer, Peter Munich, DE 106 2671
Lutterbuese, Ralf Munich, DE 15 614
Rau, Doris Munich, DE 49 1124
Raum, Tobias Munich, DE 92 1685

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