Maytansinoid derivatives

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United States of America Patent

PATENT NO 9345786
APP PUB NO 20140178414A1
SERIAL NO

13837783

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Abstract

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Disclosed herein are maytansinoid drug linker derivatives which can be linked to a antigen binding unit (Abu), and maytansinoid drugs linked with an antigen binding unit (Drug-Linker-Antigen binding Unit: D-L-Abu), for targeted delivery to disease tissues. D-L-Abu, D-L-Abu derivatives, and methods relating to the use of such drug conjugates to treat antigen positive cells in cancers and immunological disorders are provided.

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Patent Owner(s)

  • BIO-THERA SOLUTIONS, LTD., CO.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Deng, Xiaobin Guangzhou, CN 9 40
Li, Shengfeng Belmont, US 39 203
Qin, Chao Guangzhou, CN 57 236
Tan, Songnuan Guangzhou, CN 4 18
Tang, Weijia Guangzhou, CN 15 57

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