Single chain relaxin polypeptides

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United States of America Patent

PATENT NO 9359422
APP PUB NO 20140038895A1
SERIAL NO

13821726

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Abstract

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The present invention relates to biologically active single chain relaxin polypeptides comprising a relaxin B chain derived from relaxin-3, the polypeptides being truncated by one or more amino acids at the C-terminus of the relaxin-3 B chain. Typically the single chain relaxin polypeptides are antagonists of the RXFP3 receptor, and in some embodiments are selective antagonists of the RXFP3 receptor.

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Patent Owner(s)

Patent OwnerAddress
HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINEVITORIA AUSTRALIA VICTORIA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bathgate, Ross Alexander David Monee Ponds, AU 9 34
Gundlach, Andrew Lawrence Hawthorn, AU 6 10
Haugaard-Kedstrom, Linda Maria St. Lucia, AU 1 1
Hossain, Mohammed Akhter Brunswick West, AU 5 12
Lawrence, Andrew J Parkville, AU 2 6
Rosengren, Karl Johan Wilston, AU 1 1
Wade, John Desmond Parkville, AU 8 20

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