Myelin regeneration with androgens
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United States of America Patent
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Jun 14, 2016
Grant Date -
Jan 9, 2014
app pub date -
Mar 22, 2012
filing date -
Mar 22, 2011
priority date (Note) -
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Abstract
Methods for effective remyelination in patients are disclosed comprising treating the patient with an androgen receptor ligand which exerts binding to androgen receptors and elicits androgen-receptor-induced biological responses at a dosage sufficient to induce remyelination. The androgen compound preferably comprises MENT in an androgen targeting both androgen and estrogen receptors, and the methods include combining the androgen compound with a progestin compound in order to provide both contraception in men and treatment for neurodegeneration.
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