Compositions and methods of treating head and neck cancer
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United States of America Patent
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Jun 21, 2016
Grant Date -
Jul 4, 2013
app pub date -
Jul 25, 2012
filing date -
Jul 27, 2011
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Abstract
The present invention provides methods related to the treatment of head and neck squamous cell carcinoma (HNSCC) and its associated premalignant lesions. In particular, the invention features methods which may specifically target HNSCC-associated genes and alter gene expression to treat or alleviate a symptom of HNSCC, or its related premalignant lesions. These methods may involve decreasing the function of an HNSCC-associated gene with aberrant gain-of-function; or increasing the function of an HNSCC-associated gene with aberrant loss-of-function.
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