Coagulation factor VII polypeptides
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United States of America Patent
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Jun 21, 2016
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Oct 15, 2014
filing date -
Oct 15, 2013
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Abstract
The present invention relates to modified coagulation Factor VII polypeptides exhibiting increased resistance to antithrombin inactivation and enhanced proteolytic activity. The present invention also relates to polynucleotide constructs encoding such polypeptides, vectors and host cells comprising and expressing such polynucleotides, pharmaceutical compositions, uses and methods of treatment.
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