VLPS derived from cells that do not express a viral matrix or core protein
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United States of America Patent
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Jul 5, 2016
Grant Date -
Aug 21, 2014
app pub date -
Apr 14, 2014
filing date -
May 25, 2007
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Abstract
The present invention discloses novel influenza virus-like particles (VLPs) that contain chimeric proteins or influenza membrane proteins. The chimeric proteins are derived from fragments of influenza membrane proteins fused to heterologous proteins. The invention includes antigenic formulations and vaccines comprising VLPs of the invention as well as methods of making and administering VLPs to vertebrates, including methods of inducing immunity to infections, such as influenza.
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