Capsules containing high doses of levodopa for pulmonary use
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United States of America Patent
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Jul 19, 2016
Grant Date -
Nov 12, 2015
app pub date -
Dec 18, 2014
filing date -
Nov 9, 2012
priority date (Note) -
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Abstract
The present invention provides a capsule containing an inhalable powder composition wherein the composition comprises about 75% by weight or more levodopa, dipalmitoylphosphatidylcholine (DPPC) and a salt characterized by a working density of less than about 100 g/L. The invention further provides a capsule containing an inhalable powder composition wherein the composition comprises about 75% by weight or more levodopa, dipalmitoylphosphatidylcholine (DPPC) and a salt characterized by a working density of less than about 100 g/L wherein the capsule material comprises hydroxypropylmethylcellulose (HPMC) and titanium dioxide.
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