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Abstract

A method for making an emulsion using a rotating membrane device (10) including:

i) a membrane assembly (12) including a cylindrical porous surface (14) enclosing an inner chamber (16) concentrically positioned about an axis (X),ii) a vane assembly (18) including a plurality of vanes (20) extending along the axial length (L) of the porous surface (14) of the membrane assembly (12), wherein the vanes (24) comprise a shear surface (24) located within 1 mm of the porous surface (14), andiii) a vessel (22) enclosing the membrane and vane assemblies (12, 18);wherein the method includes the step of moving a dispersible liquid phase (26) through the porous surface (14) into a continuous liquid phase (28) while rotating at least one of the vane assembly (18) or membrane assembly (12) relative to the other about the axis (X) such that the shear surfaces (24) exert shear forces upon the dispersible liquid phase (26) passing through the porous surface (14) to form droplets (30) of a dispersed liquid phase having a size of 1 to 500 μm within the continuous liquid phase (28).

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First Claim