Pyrrolobenzodiazepines as unsymmetrical dimeric PBD compounds for inclusion in targeted conjugates

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United States of America Patent

PATENT NO 9399641
APP PUB NO 20150158869A1
SERIAL NO

14346006

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Abstract

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A compound with the formula I wherein: R2 is of formula II where Q is selected from OH, SH and NRN, and RN is selected from H, methyl and ethyl, as well as drug-linkers and drug-conjugates made from this compound.

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Patent Owner(s)

  • MEDIMMUNE LIMITED;SPIROGEN SARL

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Howard, Philip Wilson London, GB 126 5755

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