Purification of triphosphorylated oligonucleotides using capture tags

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United States of America Patent

PATENT NO 9399658
SERIAL NO

14007752

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Abstract

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The present invention relates to a method of preparing triphosphate-modified oligonucleotides using a capture tag. The method allows the synthesis and purification of triphosphate-modified oligonucleotides in high yield and purity suitable for pharmaceutical applications.

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Patent Owner(s)

Patent OwnerAddress
RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITÄT BONN53113 BONN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Goldeck, Marion Bonn, DE 7 7
Ludwig, Janos Goettingen, DE 13 27
Sproat, Brian Booischot, BE 6 347

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