Method of screening of therapeutic agents for K-Ras mutant driven cancers

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United States of America Patent

PATENT NO 9400281
APP PUB NO 20140147866A1
SERIAL NO

14144603

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Abstract

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Provided are compounds for inhibiting Snail-p53 binding and therapeutic agents for cancer including the compounds as an effective component. The Snail-p53 binding inhibitors induce expression of p53 in K-Ras mutant cell lines, thereby enabling effective treatment or prevention of K-Ras mutant cancer, such as, pancreatic cancer, lung cancer, cholangioma, and colon cancer, of which diagnosis or treatment is not easy.

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Patent Owner(s)

  • RAND BIO SCIENCE INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ha, Nam Chul Busan, KR 9 8
Lee, Jee Hyun Daejeon, KR 14 40
Lee, Sun Hye Busan, KR 3 1
Park, Bum Joon Busan, KR 8 13
Song, Gyu Yong Daejeon, KR 9 4

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