Optically controlled CNS dysfunction

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United States of America Patent

PATENT NO 9421258
SERIAL NO

14555048

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Abstract

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Provided herein are animals expressing light-responsive opsin proteins in the basal lateral amygdala of the brain and methods for producing the same wherein illumination of the light-responsive opsin proteins causes anxiety in the animal. Also provided herein are methods for alleviating and inducing anxiety in an animal as well as methods for screening for a compound that alleviates anxiety in an animal.

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Patent Owner(s)

  • THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Deisseroth, Karl Stanford, US 135 6299
Fenno, Lief San Francisco, US 11 358
Tye, Kay Cambridge, US 4 146

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