Pyridopyrimidine derivatives and use thereof
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United States of America Patent
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Aug 23, 2016
Grant Date -
Jun 11, 2015
app pub date -
Feb 13, 2015
filing date -
Mar 17, 2011
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Abstract
The invention provides novel substituted pyridopyrimidines represented by Formula I or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of the phosphoinositide 3′ OH kinase family (PI3K) for the treatment of inflammatory diseases, cancer, cardiovascular diseases, allergy, asthma and autoimmune disorders.
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