Modified carbocyanine dyes and their conjugates

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United States of America Patent

PATENT NO 9423323
APP PUB NO 20150218380A1
SERIAL NO

14687584

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Abstract

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Chemically reactive carbocyanine dyes incorporating an indolium ring moiety that is substituted at the 3-position by a reactive group or by a conjugated substance, and their uses, are described. Conjugation through this position results in spectral properties that are uniformly superior to those of conjugates of spectrally similar dyes wherein attachment is at a different position. The invention includes derivative compounds having one or more benzo nitrogens.

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Patent Owner(s)

  • LIFE TECHNOLOGIES CORPORATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cheung, Ching-Ying San Ramon, US 56 987
Leung, Wai-Yee San Ramon, US 71 1867
Yue, Stephen Eugene, US 112 1458

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