tRNA derived small RNAs (tsRNAs) involved in cell viability

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United States of America Patent

PATENT NO 9428537
APP PUB NO 20140323555A1
SERIAL NO

14214032

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Abstract

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The present invention features compositions and methods relating to tRNA-derived small RNAs (tsRNAs). Provided herein are oligonucleotide compositions that are complementary to tsRNAs, in particular leuCAGtsRNA, and methods of using the oligonucleotides for the regulation of respective tsRNA. Further provided are methods of inducing apoptosis through the inhibition of leuCAGtsRNA.

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THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITYBUILDING 170 3RD FLOOR MAIN QUAD P O BOX 20386 STANFORD CA 94305

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kay, Mark A Los Altos, US 80 1127
Kim, Hak kyun Palo Alto, US 13 16
Wang, Shengchun Union City, US 4 11

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