Segmenting biological structures from microscopy images

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United States of America Patent

PATENT NO 9443128
APP PUB NO 20140286562A1
SERIAL NO

14348342

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Abstract

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A method performed by one or more processors, includes: receiving an image to be segmented into one or more representations of one or more biological structures; accessing data representing a set of biological structures that are derived from other biological structures delineated in a training image, wherein the training image is associated with a level of modality that corresponds to a level of modality associated with the image to be segmented; computing a normalized cross correlation of the received image against one or more of the biological structures in the set of biological structures; generating, based on computing, seed data representing an estimate of a spatial organization of the one or more biological structures in the received image; and segmenting, based on a normalized cross correction of the received image to the seed data, the received image into the one or more representations of the one or more biological structures.

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Patent Owner(s)

  • UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Cheng Pittsburgh, US 504 3922
Ozolek, John A Pittsburgh, US 1 2
Rohde, Gustavo Kunde Pittsburgh, US 2 2
Wang, Wei Pittsburgh, US 2524 15862

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