Spheroids and multiparticulate tablets comprising them
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United States of America Patent
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Sep 20, 2016
Grant Date -
Aug 12, 2010
app pub date -
Apr 23, 2010
filing date -
Oct 4, 2002
priority date (Note) -
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Abstract
The invention relates to a directly-compressible gastro-resistant spheroid. The spheroid comprises: (i) a core containing one or more active substances; (ii) a flexible, deformable film which directly coats the aforementioned core and which comprises an enteric polymer and a mixture of saturated and/or unsaturated polyglycosylated glycerides, the fatty acids of which include at least 8 carbon atoms; and (iii) an outer water-dispersible layer containing at least one disintegrating agent. The invention further relates to multiparticular tablets comprising said spheroids.
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