Caspofungin or salts thereof with high purity, as well as preparation method and use thereof

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United States of America Patent

PATENT NO 9446091
APP PUB NO 20140128315A1
SERIAL NO

14113296

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Abstract

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Disclosed are a high purity of caspofungin or salts thereof, and a preparation method thereof, and use thereof. Disclosed are a caspofungin or salts thereof with low solvent residue and hyposaline, and a preparation process comprising: dissolving a crude product of caspofungin or salts thereof into a system of water and acetic acid, then mixing with a first organic solvent ethyl alcohol, subsequently mixing with a second organic solvent ethyl acetate, then being subject to filtration and drying together with water, to obtain caspofungin or salts thereof with high stability, low solvent residue and hyposaline.

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Patent Owner(s)

  • SHANGHAI TECHWELL BIOPHARMACEUTICAL CO., LTD.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
He, Bingming Shanghai, CN 10 47
Ji, Xiaoming Shanghai, CN 34 53
Li, Ming Shanghai, CN 1164 12536
Tang, Zhijun Shanghai, CN 22 122

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