Imidazopyridine compounds

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United States of America Patent

PATENT NO 9447090
APP PUB NO 20140088080A1
SERIAL NO

14090074

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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An excellent drug for treating or preventing cardiovascular diseases, based on cGMP production enhancing action due to soluble guanylate cyclase activating action, is provided. It was found that imidazopyridine compounds having a carbamoyl group at the 3-position and a substituent bonded at the 8-position via an oxygen atom in an imidazo[1,2-a]pyridine skeleton exhibits a cGMP production enhancing action by a potent soluble guanylate cyclase activating action, and is useful as a drug for treating or preventing various soluble guanylate cyclase-related cardiovascular diseases, thereby completing the present invention.

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Patent Owner(s)

  • ASTELLAS PHARMA INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hanazawa, Takeshi Tokyo, JP 8 71
Iida, Maiko Tokyo, JP 7 32
Imamura, Kenichiro Tokyo, JP 8 39
Imamura, Yoshimasa Tokyo, JP 15 205
Koga, Yuji Tokyo, JP 180 2201
Maeno, Kyoichi Tokyo, JP 15 132
Nozawa, Eisuke Tokyo, JP 14 104
Ohne, Kazuhiko Tokyo, JP 12 124
Sato, Ippei Tokyo, JP 19 83
Shibata, Hiroshi Tokyo, JP 264 4031
Watanabe, Tsubasa Tokyo, JP 26 90

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