Glycodendrimers of polypropyletherimine

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United States of America Patent

PATENT NO 9453040
APP PUB NO 20150126468A1
SERIAL NO

13818580

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Abstract

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A glycodendrimer comprising: a) a non-toxic dendrimer polypropyletherimine core supporting on average in the range of 9 to 64 terminal carboxylic acid groups, and b) conjugated to said core in the range of 2 to 8 amino sugars or a sulphate amino sugar selected from the group consisting of glucosamine, N-acetyl glucosamine, mannosamine, N-acetylmannosamine, galactosamine, a sulphate of any one of the same and a combination thereof, wherein each sugar is linked directly through a zero length amide bond with a residue of a terminal carboxylic acid group. The invention also extends to defined populations comprising said glycodendrimer molecules, pharmaceutical compositions comprising said molecules or populations, process for preparing the molecules and formulations, and therapeutic uses of the molecules, populations and compositions.

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Patent Owner(s)

  • IMPERIAL INNOVATIONS LIMITED

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Shaunak, Sunil Greater London, GB 11 104
Teo, Ian Alfred Greater London, GB 2 0

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