Process for the purification of a growth factor protein

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United States of America Patent

PATENT NO 9453045
APP PUB NO 20130096279A1
SERIAL NO

13638244

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Abstract

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A process of purifying the Growth Factor Protein G-CSF (Granulocyte Colony Stimulating Factor) in a purification sequence employing chromatography, comprising binding the G-CSF to Capto MMC™, which is a multimodal resin that comprises a negatively charged 2-(benzoylamino) butanoic acid ligand, at a pH from 4 to 6.2; and eluting the G-CSF at a pH greater than 6.3.

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OCTAPHARMA AGSWITZERLAND ZUG ZUG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gilljam, Gustav Skogas, SE 6 31
Tiemeyer, Maya Ladenburg, DE 3 7
Winge, Stefan Arsta, SE 26 146

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