Use of EP4 receptor antagonists in the treatment of IL-23 mediated diseases

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United States of America Patent

PATENT NO 9457084
APP PUB NO 20120316197A1
SERIAL NO

13580323

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Abstract

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This invention relates to a compound with EP4 antagonistic activity, or a pharmaceutically acceptable salt with EP4 receptor antagonistic activities, which is useful in the treatment of immune disease or allergy. This invention also relates to a compound of formula (I), (II), (III), (IV), (Va) or (Vb), or a pharmaceutically acceptable salt thereof with EP4 receptor antagonistic activities, which is useful in the treatment of immune disease or allergy. This invention also relates to a pharmaceutical composition for the treatment of immune disease or allergy which comprises a therapeutically effective amount of a compound of formula (I), (II), (III), (IV), (Va) or (Vb), or a pharmaceutically acceptable salt thereof. Further this invention relates to a method for the treatment of immune disease or allergy in an animal subject including a mammalian subject, which comprises administering to the animal subject including a mammalian subject a compound of the formula (I), (II), (III), (IV), (Va) or (Vb), or a pharmaceutically acceptable salt thereof.

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Patent Owner(s)

Patent OwnerAddress
ASKAT INC4-37-2 HIROJIHONMACHI SHOWA-KU NAGOYA 466-0841

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kanazawa, Kiyoshi Aichi, JP 12 471
Koizumi, Shinichi Aichi, JP 33 166
Nonomura, Kazuhiko Shizuoka, JP 15 140
Okumura, Takako Aichi, JP 18 34

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