Method of attaching a cell-of-interest to a microtube

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United States of America Patent

PATENT NO 9469919
APP PUB NO 20110039296A1
SERIAL NO

12918365

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Abstract

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A method of attaching a cell or a membrane-coated particle-of-interest to a microtube is provided. The method comprising: co-electrospinning two polymeric solutions through co-axial capillaries, wherein a first polymeric solution of the two polymeric solutions is for forming a shell of the microtube and a second polymeric solution of the two polymeric solutions is for forming a coat over an internal surface of the shell, the first polymeric solution is selected solidifying faster than the second polymeric solution and a solvent of the second polymeric solution is selected incapable of dissolving the first polymeric solution and wherein the second polymeric solution comprises the cell or the membrane-coated particle-of-interest, thereby attaching the cell or the membrane-coated panicle-of-interest to the microtube. Also provided are microtubes with attached, entrapped or encapsulated cells or membrane-coated particles and methods of using same.

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Patent Owner(s)

Patent OwnerAddress
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD3200004 HAIFA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Green, Michal Haifa, IL 8 18
Klein, Shiri Tel-Aviv, IL 3 1
Kuhn, Jonathan Charles Haifa, IL 8 63
Zussman, Eyal Haifa, IL 32 257

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