Mixed ligand gold(III) complexes as anti-cancer agents

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United States of America Patent

PATENT NO 9481693
SERIAL NO

14850063

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Abstract

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Gold(III) complexes with mixed ligands as anticancer agents. The gold(III) cations are coordinated to bidentate ligands having diamino functional groups: a diaminocyclohexane ligand and a 1,3-propylenediamine ligand. The diaminocyclohexane ligand can exist in both cis- and trans-configurations, resulting in isomeric gold(III) complexes. Also described are pharmaceutical compositions incorporating the gold(III) complexes, methods of synthesis, methods of treating cancer and methods of inhibiting cancer cell proliferation and inducing cancer cell apoptosis.

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Patent Owner(s)

Patent OwnerAddress
KING FAHD UNIVERSITY OF PETROLEUM AND MINERALSDHAHRAN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Al-Jaroudi, Said Qatif-Qudaih, SA 4 9
Al-Saadi, Abdulaziz Dhahran, SA 9 12
Altaf, Muhammad Dhahran, SA 44 54
Isab, Anvarhusein Abdulkadir Dhahran, SA 23 35

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