Methods and compositions comprising non-natural amino acids
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United States of America Patent
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Nov 8, 2016
Grant Date -
Jun 16, 2011
app pub date -
Oct 11, 2010
filing date -
Nov 16, 2005
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Abstract
Disclosed herein are methods of detecting non-natural amino acids and polypeptides that include at least one non-natural amino acid. The non-natural amino acids, by themselves or as a part of a polypeptide, can include a wide range of functionalities, including but not limited to oxime, carbonyl, and/or hydroxylamine groups. Also disclosed herein are non-natural amino acid polypeptides that are further modified post-translationally, and methods for detecting such polypeptides.
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