Post-charging of zeolite doped plastics with antimicrobial metal ions
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United States of America Patent
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Nov 15, 2016
Grant Date -
Dec 13, 2012
app pub date -
Nov 24, 2010
filing date -
Nov 25, 2009
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Abstract
Methods of post-loading ceramic particles with antimicrobial metal cations are disclosed. In certain embodiments, the post-loaded particles are zeolites, wherein the zeolites have been incorporated into a resin and the combination is used as an implantable device. In certain embodiments, the polymer is a thermoplastic polymer such as polyaryletheretherketone (PEEK). In certain embodiments, the source of antimicrobial activity includes ion-exchangeable cations contained in a zeolite. In certain embodiments, disclosed are methods of imparting antimicrobial activity to devices by controlling the delivery of certain cations through ion-exchange via a zeolite incorporated in the device.
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